Anti-CDC20 (IHC)

Anti-CDC20 (IHC)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00232-T 10 µl (5 µg) -

2 - 8 business days*

164.00€
IHC-00232 100 µl (50 µg) -

2 - 8 business days*

623.00€
 
Protein function: Required for full ubiquitin ligase activity of the anaphase promoting... more
Product information "Anti-CDC20 (IHC)"
Protein function: Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation. [The UniProt Consortium]
Keywords: Anti-CDC20, Anti-p55CDC, Anti-Cell division cycle protein 20 homolog
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00232

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse (Expected: dog, horse, guinea pig_10141, pig, panda, orangutan, monkey, gorilla, chimpanzee, small-eared galago, naked mole rat)
Immunogen: synthetic peptide. The epitope recognized by IHC-00232 maps to a region between residue 50 and 100 of human cell division cycle 20 using the numbering given in entry NP_001246.2 (GeneID 991).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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