Anti-Filamin A (IHC)

Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00225-T 10 µl (500 ng) -

2 - 8 business days*

164.00€
IHC-00225 100 µl (5 µg) -

2 - 8 business days*

623.00€
 
Protein function: Promotes orthogonal branching of actin filaments and links actin filaments to... more
Product information "Anti-Filamin A (IHC)"
Protein function: Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface- localized furin, modulates its rate of internalization and directs its intracellular trafficking. Involved in ciliogenesis. Plays a role in cell-cell contacts and adherens junctions during the development of blood vessels, heart and brain organs. Plays a role in platelets morphology through interaction with SYK that regulates ITAM- and ITAM-like-containing receptor signaling, resulting in by platelet cytoskeleton organization maintainance. [The UniProt Consortium]
Keywords: Anti-FLN, Anti-FLNA, Anti-FLN-A, Anti-ABP-280, Anti-Filamin-1, Anti-Filamin-A, Anti-Alpha-filamin, Anti-Non-muscle filamin, Anti-Actin-binding protein 280, Anti-Endothelial actin-binding protein
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00225

Properties

Application: IHC, IHC-IF
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: mouse, orangutan, monkey, gorilla, northern white-cheeked gibbon, olive baboon, crab-eating macaque, dusky titi monkey)
Immunogen: synthetic peptide. The epitope recognized by IHC-00225 maps to a region between residue 1725 and 1775 of human Filamin A using the numbering given in entry NP_001447.1 (GeneID 2316).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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