Anti-XRN2 (IHC)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
IHC-00223-T	10 µl (2500 ng)		-		2 - 8 business days*		164.00€
IHC-00223	100 µl (25 µg)		-		2 - 8 business days*		623.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Possesses 5'->3' exoribonuclease activity. May promote the termination of... more

Close menu

Product information "Anti-XRN2 (IHC)"

Protein function: Possesses 5'->3' exoribonuclease activity. May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription. Binds to RNA polymerase II (RNAp II) transcription termination R-loops formed by G-rich pause sites (PubMed:21700224). [The UniProt Consortium]

Keywords:	Anti-XRN2, EC=3.1.13.-, Anti-DHP protein, Anti-DHM1-like protein, Anti-5'-3' exoribonuclease 2
Supplier:	Bethyl Laboratories
Supplier-Nr:	IHC-00223

Properties

Application:	IHC, IHC-IF
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: orangutan, monkey, chimpanzee, northern white-cheeked gibbon, little brown bat, african elephant, crab-eating macaque)
Immunogen:	synthetic peptide. The epitope recognized by IHC-00223 maps to a region between residue 900 and 950 human 5'-3' exoribonuclease 2 using the numbering given in entry NP_036387.2 (GeneID 22803).
Format:	Antigen Affinity Purified