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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
IHC-00223-T | 10 µl (2500 ng) | - |
2 - 8 business days* |
164.00€
|
|||
IHC-00223 | 100 µl (25 µg) | - |
2 - 8 business days* |
623.00€
|
Protein function: Possesses 5'->3' exoribonuclease activity. May promote the termination of... more
Product information "Anti-XRN2 (IHC)"
Protein function: Possesses 5'->3' exoribonuclease activity. May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription. Binds to RNA polymerase II (RNAp II) transcription termination R-loops formed by G-rich pause sites (PubMed:21700224). [The UniProt Consortium]
Keywords: | Anti-XRN2, EC=3.1.13.-, Anti-DHP protein, Anti-DHM1-like protein, Anti-5'-3' exoribonuclease 2 |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | IHC-00223 |
Properties
Application: | IHC, IHC-IF |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse (Expected: orangutan, monkey, chimpanzee, northern white-cheeked gibbon, little brown bat, african elephant, crab-eating macaque) |
Immunogen: | synthetic peptide. The epitope recognized by IHC-00223 maps to a region between residue 900 and 950 human 5'-3' exoribonuclease 2 using the numbering given in entry NP_036387.2 (GeneID 22803). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K12619 | Matching products |
UniProt ID : | Q9H0D6 | Matching products |
Gene ID | GeneID 22803 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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