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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
IHC-00204-T | 10 µl (500 ng) | - |
2 - 8 business days* |
164.00€
|
|||
IHC-00204 | 100 µl (5 µg) | - |
2 - 8 business days* |
623.00€
|
Protein function: Seems to be involved in transcriptional silencing in heterochromatin-like... more
Product information "Anti-CBX3 (IHC)"
Protein function: Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation, mediates the recruitment of the methyltransferases SUV39H1 and/or SUV39H2 by the PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1. [The UniProt Consortium]
Keywords: | Anti-HECH, Anti-CBX3, Anti-HP1 gamma, Anti-Modifier 2 protein, Anti-Chromobox protein homolog 3, Anti-Heterochromatin protein 1 homolog gamma |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | IHC-00204 |
Properties
Application: | IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse (Expected: rat, X. laevis, X. tropicalis, chicken, turkey, bovine, dog, horse, rabbit, guinea pig_10141, pig, panda, orangutan, monkey) |
Immunogen: | synthetic peptide. The epitope recognized by IHC-00204 maps to a region between residues 133 and the C-terminus (residue 183) of human chromobox homolog 3 using the numbering given in entry NP_009207.2 (GeneID 11335). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K11586 | Matching products |
UniProt ID : | Q13185 | Matching products |
Gene ID | GeneID 11335 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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