Anti-JMJD2A (IHC)

Anti-JMJD2A (IHC)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00188-T 10 µl (2500 ng) -

2 - 8 business days*

164.00€
IHC-00188 100 µl (25 µg) -

2 - 8 business days*

623.00€
 
Protein function: Histone demethylase that specifically demethylates 'Lys- 9' and 'Lys-36'... more
Product information "Anti-JMJD2A (IHC)"
Protein function: Histone demethylase that specifically demethylates 'Lys- 9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively. [The UniProt Consortium]
Keywords: Anti-KDM4A, Anti-JHDM3A, EC=1.14.11.-, Anti-Lysine-specific demethylase 4A, Anti-Jumonji domain-containing protein 2A, Anti-JmjC domain-containing histone demethylation protein 3A
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00188

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: orangutan, gorilla, chimpanzee, crab-eating macaque, white-tufted-ear marmoset)
Immunogen: synthetic peptide. The epitope recognized by IHC-00188 maps to a region between residues 350 and 400 of human Jumonji Domain Containing 2A using the numbering given in entry NP_055478.1 (GeneID 9682).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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