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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
IHC-00173-T | 10 µl (2500 ng) | - |
2 - 8 business days* |
164.00€
|
|||
IHC-00173 | 100 µl (25 µg) | - |
2 - 8 business days* |
623.00€
|
Protein function: Multifunctional protein with various roles in different cellular compartments.... more
Product information "Anti-HMG2a (IHC)"
Protein function: Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. Associates with chromatin and binds DNA with a preference to non- canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters. Proposed to be involved in the innate immune response to nucleic acids by acting as a cytoplasmic promiscuous immunogenic DNA/RNA sensor. Negatively regulates B-cell and myeloid cell differentiation. In hematopoietic stem cells may regulate the balance between self-renewal and differentiation. Involved in negative regulation of canonical Wnt signaling. [The UniProt Consortium]
Keywords: | Anti-HMG2A, Anti-HMGB3, Anti-HMG-4, Anti-HMG-2a, Anti-High mobility group protein 4, Anti-High mobility group protein B3, Anti-High mobility group protein 2a |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | IHC-00173 |
Properties
Application: | IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse (Expected: rat, dog, horse, rabbit, guinea pig_10141, pig, panda, orangutan, monkey, gorilla, chimpanzee, crab-eating macaque) |
Immunogen: | synthetic peptide. The epitope recognized by IHC-00173 maps to a region between residues 125 and 175 of human High-Mobility Group 2A using the numbering given in entry NP_005333.2 (GeneID 3149). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K11296 | Matching products |
UniProt ID : | O15347 | Matching products |
Gene ID | GeneID 3149 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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