Anti-HMG2a (IHC)

Anti-HMG2a (IHC)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00173-T 10 µl (2500 ng) -

2 - 8 business days*

164.00€
IHC-00173 100 µl (25 µg) -

2 - 8 business days*

623.00€
 
Protein function: Multifunctional protein with various roles in different cellular compartments.... more
Product information "Anti-HMG2a (IHC)"
Protein function: Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. Associates with chromatin and binds DNA with a preference to non- canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters. Proposed to be involved in the innate immune response to nucleic acids by acting as a cytoplasmic promiscuous immunogenic DNA/RNA sensor. Negatively regulates B-cell and myeloid cell differentiation. In hematopoietic stem cells may regulate the balance between self-renewal and differentiation. Involved in negative regulation of canonical Wnt signaling. [The UniProt Consortium]
Keywords: Anti-HMG2A, Anti-HMGB3, Anti-HMG-4, Anti-HMG-2a, Anti-High mobility group protein 4, Anti-High mobility group protein B3, Anti-High mobility group protein 2a
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00173

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse (Expected: rat, dog, horse, rabbit, guinea pig_10141, pig, panda, orangutan, monkey, gorilla, chimpanzee, crab-eating macaque)
Immunogen: synthetic peptide. The epitope recognized by IHC-00173 maps to a region between residues 125 and 175 of human High-Mobility Group 2A using the numbering given in entry NP_005333.2 (GeneID 3149).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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