Anti-UBCH7 (IHC)

Anti-UBCH7 (IHC)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00148-T 10 µl (1 µg) -

2 - 8 business days*

164.00€
IHC-00148 100 µl (10 µg) -

2 - 8 business days*

623.00€
 
Protein function: Ubiquitin-conjugating enzyme E2 that specifically acts with HECT-type and RBR... more
Product information "Anti-UBCH7 (IHC)"
Protein function: Ubiquitin-conjugating enzyme E2 that specifically acts with HECT-type and RBR family E3 ubiquitin-protein ligases. Does not function with most RING-containing E3 ubiquitin-protein ligases because it lacks intrinsic E3-independent reactivity with lysine: in contrast, it has activity with the RBR family E3 enzymes, such as PRKN and ARIH1, that function like function like RING-HECT hybrids. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-linked polyubiquitination. Involved in the selective degradation of short-lived and abnormal proteins. Down- regulated during the S-phase it is involved in progression through the cell cycle. Regulates nuclear hormone receptors transcriptional activity. May play a role in myelopoiesis. [The UniProt Consortium]
Keywords: Anti-UBCE7, Anti-UbcH7, Anti-L-UBC, Anti-UBE2L3, Anti-Ubiquitin-protein ligase L3, Anti-Ubiquitin carrier protein L3, Anti-Ubiquitin-conjugating enzyme E2-F1, Anti-Ubiquitin-conjugating enzyme E2 L3, Anti-E2 ubiquitin-conjugating enzyme L3
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00148

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: mouse, rat, X. laevis, X. tropicalis, chicken, turkey, bovine, dog, horse, rabbit, guinea pig_10141, pig, panda, orangutan)
Immunogen: synthetic peptide. The epitope recognized by IHC-00148 maps to a region between residues 100 and the C-terminus (residue 154) of human Ubiquitin-Conjugating Enzyme H7 using the numbering given in entry NP_003338.1 (GeneID 7332).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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