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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
IHC-00143-T | 10 µl (2500 ng) | - |
2 - 8 business days* |
164.00€
|
|||
IHC-00143 | 100 µl (25 µg) | - |
2 - 8 business days* |
623.00€
|
Protein function: Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1... more
Product information "Anti-Sin3A (IHC)"
Protein function: Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in he control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation. Cooperates with FOXK1 to regulate cell cycle progression probably by repressing cell cycle inhibitor genes expression. [The UniProt Consortium]
Keywords: | Anti-Transcriptional corepressor Sin3a, Anti-Paired amphipathic helix protein Sin3a, Anti-Histone deacetylase complex subunit Sin3a |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | IHC-00143 |
Properties
Application: | IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse (Expected: rat, bovine, dog, horse, panda, orangutan, monkey, gorilla, chimpanzee, white-tufted-ear marmoset, crab-eating macaque) |
Immunogen: | synthetic peptide. The epitope recognized by IHC-00143 maps to a region between residues 1 and 50 of human SIN3 homolog A using the numbering given in entry NP_056292.1 (GeneID 25942). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K11644 | Matching products |
UniProt ID : | Q96ST3 | Matching products |
Gene ID | GeneID 25942 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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