Anti-SMAR1/BANP (IHC)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
IHC-00140-T	10 µl (500 ng)		-		2 - 8 business days*		164.00€
IHC-00140	100 µl (5 µg)		-		2 - 8 business days*		623.00€

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Protein function: Controls V(D)J recombination during T-cell development by repressing T-cell... more

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Product information "Anti-SMAR1/BANP (IHC)"

Protein function: Controls V(D)J recombination during T-cell development by repressing T-cell receptor (TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta (S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumulation, which causes cell cycle arrest. [The UniProt Consortium]

Keywords:	Anti-BANP, Anti-BEND1, Anti-Protein BANP, Anti-BEN domain-containing protein 1, Anti-Btg3-associated nuclear protein, Anti-Scaffold/matrix-associated region-1-binding protein
Supplier:	Bethyl Laboratories
Supplier-Nr:	IHC-00140

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: rat, bovine, dog, horse, rabbit, guinea pig_10141, panda, orangutan, monkey, chimpanzee, chinese hamster, little brown bat)
Immunogen:	synthetic peptide. The epitope recognized by IHC-00140 maps to a region between residues 425 and the C-terminus (residue 469) of human BTG3 associated nuclear protein using the numbering given in TrEMBL entry Q96GJ7 (GeneID 54971).
Format:	Antigen Affinity Purified