Anti-4EBP1 (IHC)

Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00133-T 10 µl (500 ng) -

2 - 8 business days*

164.00€
IHC-00133 100 µl (5 µg) -

2 - 8 business days*

623.00€
 
Protein function: Repressor of translation initiation that regulates EIF4E activity by preventing... more
Product information "Anti-4EBP1 (IHC)"
Protein function: Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways. [The UniProt Consortium]
Keywords: Anti-4E-BP1, Anti-PHAS-I, Anti-EIF4EBP1, Anti-eIF4E-binding protein 1, Anti-Eukaryotic translation initiation factor 4E-binding protein 1, Anti-Phosphorylated heat- and acid-stable protein regulated by insulin 1
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00133

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse (Expected: rat, rabbit, pig, orangutan, monkey, gorilla, chimpanzee, hirteen-lined ground squirrel, chinese hamster, crab-eating macaque)
Immunogen: synthetic peptide. The epitope recognized by IHC-00133 maps to a region between residues 75 and the C-terminus (residue 118) of human eukaryotic translation initiation factor 4E binding protein 1 using the numbering given in entry NP_004086.1 (GeneID 1978).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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