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Track device being used
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
IHC-00123-T | 10 µl (2500 ng) | - |
2 - 8 business days* |
164.00€
|
|||
IHC-00123 | 100 µl (25 µg) | - |
2 - 8 business days* |
623.00€
|
Protein function: Has a dual function in spindle-assembly checkpoint signaling and in promoting... more
Product information "Anti-Bub3 (IHC)"
Protein function: Has a dual function in spindle-assembly checkpoint signaling and in promoting the establishment of correct kinetochore-microtubule (K-MT) attachments. Promotes the formation of stable end-on bipolar attachments. Necessary for kinetochore localization of BUB1. Regulates chromosome segregation during oocyte meiosis. The BUB1/BUB3 complex plays a role in the inhibition of anaphase-promoting complex or cyclosome (APC/C) when spindle-assembly checkpoint is activated and inhibits the ubiquitin ligase activity of APC/C by phosphorylating its activator CDC20. This complex can also phosphorylate MAD1L1. [The UniProt Consortium]
Keywords: | Anti-BUB3, Anti-Mitotic checkpoint protein BUB3 |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | IHC-00123 |
Properties
Application: | IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human (Expected: mouse, rat, bovine, dog, horse, rabbit, guinea pig_10141, pig, panda, orangutan, monkey, gorilla, white-tufted-ear marmoset) |
Immunogen: | synthetic peptide. The epitope recognized by IHC-00123 maps to a region between residues 275 and 325 of human BUB3 using the numbering given in Swiss-Prot entry O43684 (GeneID 9184). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K02180 | Matching products |
UniProt ID : | O43684 | Matching products |
Gene ID | GeneID 9184 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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