Anti-RNF40 (IHC)

Anti-RNF40 (IHC)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00102-T 10 µl (2500 ng) -

2 - 8 business days*

164.00€
IHC-00102 100 µl (25 µg) -

2 - 8 business days*

623.00€
 
Protein function: Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates... more
Product information "Anti-RNF40 (IHC)"
Protein function: Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role in histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B, reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes. [The UniProt Consortium]
Keywords: Anti-BRE1B, Anti-RBP95, Anti-RNF40, Anti-BRE1-B, Anti-RING finger protein 40, Anti-E3 ubiquitin-protein ligase BRE1B, Anti-RING-type E3 ubiquitin transferase BRE1B, Anti-95 kDa retinoblastoma-associated protein
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00102

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: monkey, gorilla, chimpanzee, northern white-cheeked gibbon, crab-eating macaque)
Immunogen: synthetic peptide. The epitope recognized by IHC-00102 maps to a region between residue 540 and 590 of human Ring Finger 40 using the numbering given in entry NP_055586.1 (GeneID 9810).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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