Anti-hnRNP-K (IHC)

Anti-hnRNP-K (IHC)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00088-T 10 µl (500 ng) -

2 - 8 business days*

164.00€
IHC-00088 100 µl (5 µg) -

2 - 8 business days*

623.00€
 
Protein function: One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C)... more
Product information "Anti-hnRNP-K (IHC)"
Protein function: One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single- stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction. As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest. [The UniProt Consortium]
Keywords: Anti-TUNP, Anti-HNRPK, Anti-HNRNPK, Anti-hnRNP K, Anti-Heterogeneous nuclear ribonucleoprotein K, Anti-Transformation up-regulated nuclear protein
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00088

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse (Expected: rat, bovine, guinea pig_10141, panda, orangutan, monkey, gorilla, naked mole rat, gray short-tailed opossum)
Immunogen: synthetic peptide. The epitope recognized by IHC-00088 maps to the C-terminus specific for isoform a of human Heterogeneous Nuclear Ribonucleoprotein K using the numbering given in entry NP_002131.2 for human hnRNP-K isoform b (GeneID 3190).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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