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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
IHC-00078-T | 10 µl (2500 ng) | - |
2 - 8 business days* |
164.00€
|
|||
IHC-00078 | 100 µl (25 µg) | - |
2 - 8 business days* |
623.00€
|
Protein function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to... more
Product information "Anti-Rad6 (IHC)"
Protein function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11', as well as 'Lys-48'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA. [The UniProt Consortium]
Keywords: | Anti-HR6A, Anti-RAD6A, Anti-UBE2A, Anti-hHR6A, Anti-RAD6 homolog A, Anti-Ubiquitin-protein ligase A, Anti-Ubiquitin carrier protein A, Anti-E2 ubiquitin-conjugating enzyme A, Anti-Ubiquitin-conjugating enzyme E2 A |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | IHC-00078 |
Properties
Application: | IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse (Expected: rat, D. melanogaster, zebrafish, X. laevis, X. tropicalis, chicken, bovine, horse, rabbit, guinea pig_10141, pig, panda) |
Immunogen: | synthetic peptide. The epitope recognized by IHC-00078 maps to the N-terminus of human ubiquitin-conjugating enzyme E2A using the numbering given in Swiss-Prot entry P49459 (GeneID 7319). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K10573 | Matching products |
UniProt ID : | P49459 | Matching products |
Gene ID | GeneID 7319 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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