Anti-Rad6 (IHC)

Anti-Rad6 (IHC)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00078-T 10 µl (2500 ng) -

2 - 8 business days*

164.00€
IHC-00078 100 µl (25 µg) -

2 - 8 business days*

623.00€
 
Protein function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to... more
Product information "Anti-Rad6 (IHC)"
Protein function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11', as well as 'Lys-48'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA. [The UniProt Consortium]
Keywords: Anti-HR6A, Anti-RAD6A, Anti-UBE2A, Anti-hHR6A, Anti-RAD6 homolog A, Anti-Ubiquitin-protein ligase A, Anti-Ubiquitin carrier protein A, Anti-E2 ubiquitin-conjugating enzyme A, Anti-Ubiquitin-conjugating enzyme E2 A
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00078

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse (Expected: rat, D. melanogaster, zebrafish, X. laevis, X. tropicalis, chicken, bovine, horse, rabbit, guinea pig_10141, pig, panda)
Immunogen: synthetic peptide. The epitope recognized by IHC-00078 maps to the N-terminus of human ubiquitin-conjugating enzyme E2A using the numbering given in Swiss-Prot entry P49459 (GeneID 7319).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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