Anti-NCOA2/SRC2 (IHC)

Anti-NCOA2/SRC2 (IHC)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00030-T 10 µl (2500 ng) -

2 - 8 business days*

164.00€
IHC-00030 100 µl (25 µg) -

2 - 8 business days*

623.00€
 
Protein function: Transcriptional coactivator for steroid receptors and nuclear receptors.... more
Product information "Anti-NCOA2/SRC2 (IHC)"
Protein function: Transcriptional coactivator for steroid receptors and nuclear receptors. Coactivator of the steroid binding domain (AF- 2) but not of the modulating N-terminal domain (AF-1). Required with NCOA1 to control energy balance between white and brown adipose tissues. Critical regulator of glucose metabolism regulation, acts as RORA coactivator to specifically modulate G6PC expression. Involved in the positive regulation of the transcriptional activity of the glucocorticoid receptor NR3C1 by sumoylation enhancer RWDD3. Positively regulates the circadian clock by acting as a transcriptional coactivator for the CLOCK- ARNTL/BMAL1 heterodimer. [The UniProt Consortium]
Keywords: Anti-hTIF2, Anti-NCOA2, Anti-NCoA-2, Anti-bHLHe75, Anti-BHLHE75, Anti-Nuclear receptor coactivator 2, Anti-Transcriptional intermediary factor 2, Anti-Class E basic helix-loop-helix protein 75
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00030

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: monkey, gorilla, chimpanzee, northern white-cheeked gibbon, white-tufted-ear marmoset)
Immunogen: synthetic peptide. The epitope recognized by IHC-00030 maps to a region between residue 1400 and the C-terminus (residue 1464) of human Nuclear Receptor Coactivator 2 using the numbering given in entry NP_006531.1 (GeneID 10499).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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