Anti-CoAA (IHC)

Anti-CoAA (IHC)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00024-T 10 µl (5 µg) -

2 - 8 business days*

164.00€
IHC-00024 100 µl (50 µg) -

2 - 8 business days*

623.00€
 
Protein function: Isoform 1 may function as a nuclear receptor coactivator, enhancing... more
Product information "Anti-CoAA (IHC)"
Protein function: Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1 (PubMed:11443112). Regulates centriole biogenesis by suppressing the formation of aberrant centriolar protein complexes in the cytoplasm and thus preserving mitotic spindle integrity. Prevents the formation of the STIL-CENPJ complex (which can induce the formation of aberrant centriolar protein complexes) by interfering with the interaction of STIL with CENPJ (PubMed:25385835). Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway (PubMed:28712728). [The UniProt Consortium]
Keywords: Anti-SIP, Anti-PSP2, Anti-RBM14, Anti-Paraspeckle protein 2, Anti-RNA-binding protein 14, Anti-SYT-interacting protein, Anti-RNA-binding motif protein 14, Anti-Synaptotagmin-interacting protein, Anti-RRM-containing coactivator activator/modulator
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00024

Properties

Application: IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human (Expected: guinea pig_10141, orangutan, monkey, gorilla, chimpanzee, northern white-cheeked gibbon, crab-eating macaque)
Immunogen: synthetic peptide. The epitope recognized by IHC-00024 maps to a region between residue 150 and 200 of human Coactivator Activator (RNA Binding Motif Protein 14) using the numbering given in entry NP_006319.1 (GeneID 10432).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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