Anti-phospho-MCM2 (Ser108) (IHC)

Item number Size Datasheet Manual SDS Delivery time Quantity Price
IHC-00014-T 10 µl (1 µg) -

2 - 8 business days*

164.00€
IHC-00014 100 µl (10 µg) -

2 - 8 business days*

665.00€
 
Protein function: Acts as component of the MCM2-7 complex (MCM complex) which is the putative... more
Product information "Anti-phospho-MCM2 (Ser108) (IHC)"
Protein function: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division. Plays a role in terminally differentiated hair cells development of the cochlea and induces cells apoptosis. [The UniProt Consortium]
Keywords: Anti-phospho-BM28, Anti-phospho-MCM2, EC=3.6.4.12, Anti-phospho-Nuclear protein BM28, Anti-phospho-DNA replication licensing factor MCM2, Anti-phospho-Minichromosome maintenance protein 2 homolog
Supplier: Bethyl Laboratories
Supplier-Nr: IHC-00014

Properties

Application: IHC, IHC-IF
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse (Expected: rat, chicken, turkey, bovine, dog, horse, rabbit, guinea pig_10141, pig, panda, orangutan, monkey, gorilla, chimpanzee)
Immunogen: synthetic peptide. Immunogen for IHC-00014 was a synthetic phosphorylated peptide, which represented a portion of human Minichromosomal Maintenance Deficient 2 surrounding Serine 108 according to the numbering given in entry NP_0045117.2 (GeneID 4171).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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