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Anti-NEDD4L

ART NR.: A302-512A (100 µl)

Hersteller: Bethyl

Datenblatt

Anwendungen: WB, IP

Format: antigen affinity purified

Wirt: Rabbit

Isotyp: IgG

Reaktivität: human, mouse

Immunogen: synthetic peptide. The epitope recognized by A302-512A maps to a region between residue 225 and 275 of human neural precursor cell expressed, developmentally down-regulated 4-like using the numbering given in entry NP_001138439.1 (GeneID 23327).

UniProt ID: Q96PU5
Suche mit UniProt ID

Geninformationen: GeneID 23327

Schlagworte: EC=6.3.2.-, Anti-NEDD4L, Anti-neural precursor cell expressed, Anti-developmentally down-regulated 4-like, Anti-RSP5.

100 µl

349 €

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Bemerkungen: NEDD4L (neural precursor cell expressed, developmentally down-regulated 4-like) functions as an E3 ubiquitin-protein ligase. NEDD4L inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation. It also promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5. Alternative names for NEDD4L include ubiquitin-protein ligase Rsp5, Nedd4-2, Nedd4.2, NEDL3, and KIAA0439.

Die Preise für Antikörper verstehen sich exkl. Versandkosten, eventuell anfallender Kühlmittelpauschale sowie der jeweils geltenden Mehrwertsteuer.





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