Anti-HERC1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A301-904A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A301-904A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Involved in membrane trafficking via some guanine nucleotide exchange factor... more

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Product information "Anti-HERC1"

Protein function: Involved in membrane trafficking via some guanine nucleotide exchange factor (GEF) activity and its ability to bind clathrin. Acts as a GEF for Arf and Rab, by exchanging bound GDP for free GTP. Binds phosphatidylinositol 4,5-bisphosphate, which is required for GEF activity. May also act as a E3 ubiquitin- protein ligase which accepts ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. [The UniProt Consortium]

Keywords:	Anti-p619, Anti-p532, Anti-HERC1, EC=2.3.2.26, Anti-HECT-type E3 ubiquitin transferase HERC1, Anti-Probable E3 ubiquitin-protein ligase HERC1, Anti-HECT domain and RCC1-like domain-containing protein 1
Supplier:	Bethyl Laboratories
Supplier-Nr:	A301-904A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: rhesus monkey, gorilla, chimpanzee, white-tufted-ear marmoset, crab-eating macaque, small-eared galago, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A301-904A maps to a region between residue 2400 and 2450 of human hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1 using the numbering given in entry NP_003913.3 (GeneID 8925).
Format:	Antigen Affinity Purified