FBW7 (F-box and WD repeat domain containing 7) is a member of the F-box family of proteins. The F-box is a protein-protein interaction motif first identified in cyclin F. F-box proteins associate with SCFs (Skp1-cullin-F-box protein ligase complexes) which are E3 ligases that ubiquitinate proteins and target them for proteasomal degradation. FBW7 has been found to bind and specifically target cyclin E and the Notch intracellular domain (NICD) for ubiquitination. Defects in FBW7 may contribute to tumorigenesis. Alternate names for FBW7 include F-box protein FBX30, hCdc4, archipelago homolog, hAgo, SEL-10, FBXW7, and FBXO30.
Immunogen: synthetic peptide. The epitope recognized by A301-721A maps to a region between residue 50 and 100 of human F-box and WD-40 domain protein 7 using the numbering given in entry NP_361014.1 (GeneID 55294).
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Kat #: A301-721A
Menge: 100 µlBuy Bulk
Preis: 343 €
UniProt ID: Q969H0 (Protein knowledgebase)
Antikörper-Konjugations-Kits
Schlagworte:
Anti-FBW7, Anti-FBXW7, Anti-F-box and WD-40 domain protein 7, Anti-Archipelago, Anti-SEL10, Anti-SEL-10., antibody, antibodies, Antikörper Loading ...
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| Weitere Produkte für dieses Protein:Antibodies
- Anti-cdc4 (69 kDa isoform), Kat #: IMG-4118
- Anti-FBW7, Kat #: A301-720A
- Anti-FBW7 (IHC), Kat #: IHC-00348
- Anti-FBW7 (N), Kat #: AC-R0930-1
- Anti-FBXW7 (F-box and WD 40 Domain Protein 7, F-box and WD-40 Domain Protein 7, F-box and WD-40 Domain-containing Protein 7, F-box Protein FBW7, F-box/WD Repeat Protein 7, F-box/WD-repeat Protein 7, FBW7, Archipelago Drosophila Homolog of, Archipelago Hom, Kat #: F0024-77B.100
- Anti-FBXW7 (F-box and WD 40 Domain Protein 7, F-box and WD-40 Domain Protein 7, F-box and WD-40 Domain-containing Protein 7, F-box Protein FBW7, F-box/WD Repeat Protein 7, F-box/WD-repeat Protein 7, FBW7, Archipelago Drosophila Homolog of, Archipelago Hom, Kat #: F0024-77A.100
- Anti-FBXW7 (F-box and WD Repeat Domain Containing 7, F-box/WD Repeat-containing Protein 7, FBW7, Archipelago Homolog, AGO, hAgo, CDC4, hCdc4, F-box and WD-40 Domain-containing Protein 7, F-box Protein FBX30, FBX30, FBXO30, FBXW6, FBW6, SEL10, SEL-10), Kat #: F0024-77E.100
- Anti-FBXW7 (F-box and WD-40 Domain Protein 7, F-box and WD-40 Domain-containing Protein 7, F-box Protein FBW7, F-box/WD Repeat Protein 7, FBW7, Archipelago Drosophila Homolog of, Archipelago Homolog, AGO, CDC4, DKFZp686F23254, F-box Protein FBX30, FBX30, , Kat #: F0024-77D.100
- Anti-FBXW7 (monoclonal) (M02), Kat #: WA-AT2023a
- FBW7 Antibody AbVantage(TM) Pack, Kat #: A310-612A
siRNA
Primers
Products for: FBXW7, SEL10 - F-box and WD-40 domain protein 7
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