Kontakt 0800-2466651 DE | EN Merkliste Login Warenkorb
Suche
zurück

Anti-FBW7

ART NR.: A301-721A (100 µl)

Hersteller: Bethyl

Datenblatt

Anwendungen: IP

Format: antigen affinity purified

Wirt: Rabbit

Isotyp: IgG

Reaktivität: human (expected: rhesus monkey, gorilla, chimpanzee, crab-eating macaque, northern white-cheeked gibbon)

Immunogen: synthetic peptide. The epitope recognized by A301-721A maps to a region between residue 50 and 100 of human F-box and WD-40 domain protein 7 using the numbering given in entry NP_361014.1 (GeneID 55294).

UniProt ID: Q969H0
Suche mit UniProt ID

Schlagworte: Anti-FBW7, Anti-FBXW7, Anti-F-box and WD-40 domain protein 7, Anti-Archipelago, Anti-SEL10, Anti-SEL-10.

A301-721A

100 µl

349 €

In Warenkorb aufnehmen


Bemerkungen: FBW7 (F-box and WD repeat domain containing 7) is a member of the F-box family of proteins. The F-box is a protein-protein interaction motif first identified in cyclin F. F-box proteins associate with SCFs (Skp1-cullin-F-box protein ligase complexes) which are E3 ligases that ubiquitinate proteins and target them for proteasomal degradation. FBW7 has been found to bind and specifically target cyclin E and the Notch intracellular domain (NICD) for ubiquitination. Defects in FBW7 may contribute to tumorigenesis. Alternate names for FBW7 include F-box protein FBX30, hCdc4, archipelago homolog, hAgo, SEL-10, FBXW7, and FBXO30.

Spezifikationen

bethyl_datasheet_parse.php?nr=A301-721A&ak=1
Loading Loading ...

Verwandte Produkte

    Products for: FBXW7, SEL10 - F-box and WD-40 domain protein 7

    Die Preise für Antikörper verstehen sich exkl. Versandkosten, eventuell anfallender Kühlmittelpauschale sowie der jeweils geltenden Mehrwertsteuer.





    alle Treffer anzeigen (273 INFOS)

     


    Forschungsprodukte im Fokus
     
    Produkte
    Service
    Company
    € 10 Gutschein sichern