Anti-CDC20

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A301-179A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A301-179A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Required for full ubiquitin ligase activity of the anaphase promoting... more

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Product information "Anti-CDC20"

Protein function: Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation. [The UniProt Consortium]

Keywords:	Anti-CDC20, Anti-p55CDC, Anti-Cell division cycle protein 20 homolog
Supplier:	Bethyl Laboratories
Supplier-Nr:	A301-179A

Properties

Application:	WB, IP, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: pig)
Immunogen:	synthetic peptide. The epitope recognized by A301-179A maps to a region between residue 50 and 100 of human cell division cycle 20 using the numbering given in entry NP_001246.2 (GeneID 991).
Format:	Antigen Affinity Purified