Anti-MKRN1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A300-990A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A300-990A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties... more

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Product information "Anti-MKRN1"

Protein function: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. These substrates include FILIP1, p53/TP53, CDKN1A and TERT. Keeps cells alive by suppressing p53/TP53 under normal conditions, but stimulates apoptosis by repressing CDKN1A under stress conditions. Acts as a negative regulator of telomerase. Has negative and positive effects on RNA polymerase II-dependent transcription. [The UniProt Consortium]

Keywords:	Anti-MKRN1, Anti-RNF61, EC=2.3.2.27, Anti-RING finger protein 61, Anti-E3 ubiquitin-protein ligase makorin-1, Anti-RING-type E3 ubiquitin transferase makorin-1
Supplier:	Bethyl Laboratories
Supplier-Nr:	A300-990A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: mouse)
Immunogen:	synthetic peptide. The epitope recognized by A300-990A maps to a region between residue 432 and the C-terminus (residue 482) of human makorin, ring finger protein, 1 using the numbering given in entry NP_038474.1 (GeneID 23608).
Format:	Antigen Affinity Purified