Anti-Rad6

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A300-281A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A300-281A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to... more

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Product information "Anti-Rad6"

Protein function: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11', as well as 'Lys-48'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA. [The UniProt Consortium]

Keywords:	Anti-HR6A, Anti-RAD6A, Anti-UBE2A, Anti-hHR6A, Anti-RAD6 homolog A, Anti-Ubiquitin-protein ligase A, Anti-Ubiquitin carrier protein A, Anti-E2 ubiquitin-conjugating enzyme A, Anti-Ubiquitin-conjugating enzyme E2 A
Supplier:	Bethyl Laboratories
Supplier-Nr:	A300-281A

Properties

Application:	WB, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: rat, D. melanogaster, bovine, rabbit)
Immunogen:	synthetic peptide. The epitope recognized by A300-281A maps to the N-terminus of human ubiquitin-conjugating enzyme E2A using the numbering given in Swiss-Prot entry P49459 (GeneID 7319).
Format:	Antigen Affinity Purified