Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| A300-013A-T | 10 µl (10 µg) | - |
2 - 8 business days* |
164.00€
|
|||
| A300-013A | 100 µl (100 µg) | - |
2 - 8 business days* |
588.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Component of the COP9 signalosome complex (CSN), a complex involved in various... more
Product information "Anti-CSN4"
Protein function: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. Also involved in the deneddylation of non-cullin subunits such as STON2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1, IRF8/ICSBP and SNAPIN, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. [The UniProt Consortium]
| Keywords: | Anti-CSN4, Anti-SGN4, Anti-COPS4, Anti-Signalosome subunit 4, Anti-COP9 signalosome complex subunit 4, Anti-JAB1-containing signalosome subunit 4 |
| Supplier: | Bethyl Laboratories |
| Supplier-Nr: | A300-013A |
Properties
| Application: | WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, mouse (Expected: mouse, rat, bovine, pig, orangutan) |
| Immunogen: | synthetic peptide. The epitope recognized by A300-013A maps to a region between residues 350 and the C-terminus (residue 406) of human COP9 constitutive photomorphogenic homolog subunit 4 using the numbering given in entry NP_057213.2 (GeneID 51138). |
| Format: | Antigen Affinity Purified |
Database Information
| KEGG ID : | K12178 | Matching products |
| UniProt ID : | Q9BT78 | Matching products |
| Gene ID | GeneID 51138 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed