- Search results for Cay10006788
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3 products were found matching "Cay10006788"!
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Item number: Cay10006788-250
Prostaglandin D synthase (PGDS) catalyzes the isomerization of PGH2 to produce PGD2. PGD2 induces sleep, regulates nociception, inhibits platelet aggregation, and acts as an allergic mediator. Two distinct types of PGDS have been identified, namely the lipocalin-type enzyme and the hematopoietic enzyme. L-PGDS is...
Keywords: | PDS, PGDS, PGDS, PTGDS, PGDS2, PGDS2, Cerebrin-28, Cerebrin-28, PGD2 synthase, PGD2 synthase, Beta-trace protein,... |
Application: | Enzyme activity |
MW: | 46 kD |
642.00€
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Item number: Cay15129-1
Microsomal prostaglandin E synthase-1 (mPGES-1) converts the COX product PGH2 into the biologically active PGE2. Like COX-2, the expression of mPGES-1 is induced in response to pro-inflammatory mediators, including LPS, IL-1beta, and TNF-alpha. CAY10678 is a benzoimidazole that potently inhibits human and rat...
Keywords: | mPGES-1 Inhibitor III, N-cyclopentyl-1-[5,6-dimethyl-1-(1-methylethyl)-1H-benzimidazol-2-yl]-4-piperidinecarboxamide |
Application: | mPGES-1 inhibitor |
CAS | 1268709-57-4 |
MW: | 382.5 D |
From 84.00€
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Item number: Cay10006778-1
Nitrotyrosine is a post-translational modification that is formed by the nitration of tyrosine. Under conditions of oxidative stress, tyrosine is oxidized by reactive oxygen species (ROS) or, in the presence of hydrogen peroxide and nitrite, by myeloperoxidase (MPO) to yield a tyrosine radical that reacts with...
Keywords: | 3-Nitrotyrosine, NT |
Application: | WB |
Host: | Rabbit |
374.00€
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